CHM® 2 ml 8-425 neck autosampler vials, caps and septa are compatible with all common autosamplers including Agilent, Waters, Shimadzu, etc. These smaller opening vials with an 8-425 thread size screw cap are uniformly flat bottom for security with the inserts. PTFE/Silicone septa are most popular for HPLC applications, and pre-slit septa are easier to pierce with needles.CHM® 2 ml 9-425 Vials are uniformly flat bottom for security with inserts. It is equivalent in dimensions to 11 mm crimp top vials and 10-425 screw vials and can be used in the same autosampler. Can be used on all common autosamplers due to their geometry, including Agilent, HTA, Shimadzu, Thermo, Varian, Waters, etc.